BSMS > Research > Clinical and experimental medicine > Brighton and Sussex CTU > Current Studies

Current studies

The Brighton and Sussex Clinical Trials Unit is currently supporting the following studies:

Outdoor swimming as a nature-based intervention, offered in addition to usual care, compared to a group receiving usual care alone, in people with depression: a full-scale Randomised Controlled Trial

Acronym: Outside 2

Trial status: Recruiting

Disease area: Mental health

Funder: National Institute for Health and Care Research (NIHR)

FIND OUt MORE ABOUT Outside 2 >

BACKGROUND IMAGE FOR PANEL

Impact of duration of antibiotic therapy on effectiveness, safety and selection of antibiotic resistance in adult women with urinary tract infections (UTI): a randomised controlled trial

Acronym: DURATION-UTI

Trial status: Recruiting

Disease area: Infection

Funder: National Institute for Health and Care Research (NIHR)

More about DURATION-UTI study >

BACKGROUND IMAGE FOR PANEL

Palliative Long-term Abdominal Drains Versus Repeated Drainage in Untreatable Ascites Due to Advanced Cirrhosis: A Randomised Controlled Trial (REDUCe 2 Study)

Acronym: REDUCe2

Trial status: Recruiting

Disease area: Hepatology

Funder: National Institute for Health and Care Research (NIHR), Health Technology Assessment (HTA) Programme

more about the REDUCe2 study >

A Randomised Controlled Trial of an Online Intervention to Prevent Anxiety in the Children of Anxious Parents

Acronym: PWA

Trial status: Closed

Disease area: Anxiety

Funder: The Kavli Foundation

More about the PWA study >

BACKGROUND IMAGE FOR PANEL

Increasing access to CBT for psychosis patients: a randomized controlled trial evaluating brief, targeted CBT for distressing voices delivered by Assistant Psychologists

Acronym: GiVE3

Trial status: Closed

Disease area: Mental Health

Funder: National Institute for Health and Care Research (NIHR), Research for Patient Benefit (RfPB)

More about the GIVE3 study >

Evaluating the Home-based Intervention Strategy (HIS-UK) to reduce new chlamydia infection among young men aged 16-25 years by promoting correct and consistent condom use: What is the cost effectiveness of two different delivery models (face-to-face and digital delivery)?

Acronym: HIS UK

Trial status: Closed

Disease area: Sexual health/ infection

Funder: National Institute for Health and Care Research (NIHR), Public Health Research (PHR) Programme

more about the HIS UK Study >

BACKGROUND IMAGE FOR PANEL

A Phase IV Randomised, Open-Label Pilot Study to Evaluate Switching from Protease-Inhibitor based regimen to Bictegravir/Emtricitabine/Tenofovir Alafenamide Single Tablet Regimen in Integrase Inhibitor-naïve, virologically suppressed HIV-1 infected adults harbouring drug resistance mutations

Acronym: PIBIK STUDY

Trial status: Closed

Disease area: Virologically suppressed HIV-1 infected adults harbouring drug resistance mutations

Funder: Gilead Sciences, Inc

MORE ABOUT THE PIBIK STUDY >

BACKGROUND IMAGE FOR PANEL

Completed studies

CHILLY-AF
A randomised comparison of cardioversion and catheter cryoablation in patients with persistent atrial fibrillation.

EndoPredict

The Use of a prognostic tool (EndoPredict®) to inform adjuvant chemotherapy decisions in low to medium risk Oestrogen Receptor Positive, Her-2 Negative Early Breast cancer: Feasibility, Acceptability and Economic impact in Multicentre UK NHS Practice.

EVIDEnT

Laboratory observational Ex-Vivo study to investigate the sensitivity and specificity of a smart dressing to detect clinically relevant wound infection.

EYE-2

The Early Youth Engagement in first episode psychosis (EYE-2) study: pragmatic cluster randomised controlled trial of implementation, effectiveness & cost effectiveness of a team-based motivational engagement intervention to improve engagement.

HEPMARC

A phase IV, open-label, pilot study investigating non-invasive markers of hepatic fibrosis in people living with HIV-1 and non-alcoholic fatty liver disease randomised to receiving optimised background therapy (OBT) plus maraviroc or OBT.

HiFlo ASA

High Flow humidified oxygen as an early intervention in children with Acute Severe Asthma: a feasibility study.

HYVET-2

A Phase IV, Multi-Centred, Open Label, Randomised Study Assessing the Cardiovascular Outcomes Following Treatment of White Coat Hypertension with Established Anti-Hypertensive Drugs versus Standard of Care in the Very Elderly – Feasibility Study.

LIGHTMind 2

Low-Intensity Guided Help Through Mindfulness: A randomised controlled trial comparing supported mindfulness-based cognitive therapy self-help to supported cognitive behaviour therapy self-help for adults experiencing depression.

OpSal

How can we optimise inhaled beta2 agonist dose as 'reliever' medicine for wheezy pre-school children?

REDUCe

Palliative long-term abdominal drains versus repeated drainage in individuals with untreatable ascites due to advanced cirrhosis: a feasibility randomised controlled trial.

RIIiO

Pilot study for a randomised trial comparing the influence of forced air versus resistive fabric warming technologies on post-operative infection rates following orthopaedic implant surgery in adults.